Treatment of Burns

Burns are the damage of organism tissues appeared due to the high temperature (scald) or chemical agents. Treatment of skin burns is prescribed depending on the injured area of internal skin coverings (burns of the 1,2,3,4 degree) and localization (face burn, gullet burn etc.). The first aid after burn is to stop the exposures and to treat the wound. Skin after burn needs a gradual recovery.

After burns treatment includes taking medicine, physical and psychological rehabilitation.

For the burns treatment in surgical practice a method of dermaplastic is used that is based upon the patient’s own skin. In the case of lack of the patient’s own skin some other approaches should be found.

The most advanced method for the present day is cellular technologies in cambustiology for trophic ulcer and nonhealing wound treatment.

Using a method of cultivated keratinocytes (differentiated skin stem cells) it is possible to cover the top of the wound, which is several times bigger than the area taken for skin biopsy transplantation.

The basis of ceratinocyte cultivation method is culturing the fair-sized ecderonic strata from a small (several cm) flake that later are transplanted on the traumatic bed. Possibility of transplantation of such cultures for skin renovation in vivo is based on several preconditions. First of all after epidermis disaggregation and gaining cellular suspension ceratinocytes are able to create unconvertible epithelial strata in the culture, which are similar in structure to the standard ones with abilities for differentiation and morphogenesis (formation of laminated strata). Secondly they can be entirely detached from the surface of cultural bottle and transferred upon the wound. Thirdly epithelial strata are able to get implanted on the correctly prepared wound surface and create the tight junction with substructure.

Besides thermal injuries there are other disorders of the cutaneous covering integrity for the treatment of which the cultivated sells may be used. For instance, dermal equivalent is successfully used for trophic ulcer and nonhealing wound treatment. Dermal equivalent corresponds 3D collagen gel with inserted fetal human fibroblasts.

Cultivated fetal fibroblasts influence the wound heeling and epithelization due to its ability to produce collagens of various types: fibronectin, tenascin, laminin, nidogen, hondroitin-4-sulfate, growth factors (EGF и KGF). Collagen as a compound component of equivalent takes part in preparing of the wound bed, regulates chemical wound structure, advantages to migration and cell proliferation, participates in new capillaries formation, prevents cicatrisation.

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Stem cell therapy course includes:

• The bone marrow intake. The first hospitalization will take 3 days: examination for the presence of any contraindications; the intake of the bone marrow out of the iliac bone of the patient
• The first injection. We invite the patient for the first injection in 2-3 weeks (the exact time is individual and depends on the proliferate growth of stem cells culture). The hospitalization will take 2 days.
• The second injection. Usually takes place in 3-6 month after the first injection (the exact time depends on clinical indications). The hospitalization will take 2 days.
• The third injection. Usually takes place in 3-6 month after the second injection (the exact time depends on clinical indications). The hospitalization will take 2 days.

Cost of Stem Cell Therapy Course