Osteoblasts

Osteoblasts are bone-forming cells, which constitute human skeleton. These cells are “embedded” into the spongy connective tissue (see the picture). During life activity osteoblasts produce protein and mineral substances defining such unique bone properties as bone strength and fracture resistance.

It is quite sophisticated process to extract osteoblasts from adult bone tissue, since chemical agents applied for removal of minerals destroy a cell itself. Human bone marrow and periosteum – a bone coverage are the natural “bank” of osteoblasts. However, this fact doesn’t have any practical value since osteoblasts are not prone to growth and generation in vitro. Thus, the single applicable way to receive osteoblasts in a big amount is to cultivate them from stromal stem cells by means of so-called directive differentiation. Owing to unique laboratory equipment and rich experience of BIOSTEM specialists, the above-mentioned biotechnological procedure forces the growth of osteoblasts for the following cellular therapy.

BIOSTEM specialists have a successful experience of application of osteoblasts for various diseases of musculoskeletal system, such as false joints, ununited fractures and bone defects after oncotomy.